Effect of Single-Strand Break on Holliday Junction Migration Dynamics: A Single-Molecule Fluorescence Study
نویسندگان
چکیده
منابع مشابه
Holliday junction dynamics and branch migration: single-molecule analysis.
The Holliday junction (HJ) is a central intermediate in various genetic processes including homologous and site-specific recombination and DNA replication. Branch migration allows the exchange between homologous DNA regions, but the detailed mechanism for this key step of DNA recombination is unidentified. Here, we report direct real-time detection of branch migration in individual molecules. U...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2009
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2008.12.1445